AZD4547 ustat CAS Number: 268203-93-6

CAS Number: 268203-93-6

Optimizing management of ruxolitinib in patients with myelofibrosis: the need for individualized dosing

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PubMed Central PMCID: PMC5142825

RIPK2 inhibitor-1

AZD4547 ustat CAS Number: 268203-93-6AZD4547 is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. FGFR inhibitor AZD4547 binds to and inhibits FGFR, which may result in the inhibition of FGFR related signal transduction pathways, and, so, the inhibition of tumor cell proliferation and tumor cell death. FGFR, up regulated in many tumor cell types, is a receptor tyrosine kinase essential to tumor cellular proliferation,